;10/26 Chapter 17 (Part 1) • Gene Expression = transcription + translation • Tatum and Beadle o One gene = one enzyme = one protein • Central Dogma o DNA makes RNA makes protein • Transcription and Translation o DNA to RNA is transcription o RNA to protein is translation o Eukaryotic vs. Prokaryotic RNA processing, primary transcript Prokaryotes do not have nuclei so when they make RNA from DNA it is not sequestered in the nucleus. Eukaryotes Transcription occurs in the nucleus. • The RNA that leaves the nucleus is not an exact copy of the DNA. It is processed. o RNA uses U instead of T. RNA is the exact base pair set for the template strand. o The genetic code Any of the three sets of nucleotides will translate into an amino acid. 4 bases 20 amino acids o Triplet code = codons Each codon codes for specific amino acid. o Template strand Codine strand. 3’ to 5’ direction. RNA is read 5’ to 3’ o 64 = 61 + 3 • Redundant, universal, but not ambiguous o Redundancy is where four different codons code for baline. Never code for anything else. o Ambiguity o Universality Can express a gene from any organism in any other organisms. Example
Вопрос национальной безопасности. Консьерж покачал головой: - Невозможно. Быть может, вы оставите… - Всего на одну минуту. Она в столовой.